BRIEF REPORTS Lateralized P3 Deficit in Schizotypal Personality Disorder
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چکیده
Background: Reduced, left-lateralized P3 amplitude has been reported in several studies focusing on electrophysiologic function in schizophrenia. Also, several lines of evidence suggest a similarity between schizophrenia and schizotypal personality disorder (SPD). This study was undertaken to determine the replicability of our previous finding of a left-lateralized P3 amplitude deficit in SPD. Methods: We recorded event-related potentials in 21 SPD and 18 normal control subjects in an auditory “oddball” P3 paradigm. Results: In the SPD subjects, but not in the control subjects, there was lower P3 amplitude at T3 compared with T4. Conclusions: These results are similar to the ones in our previous work and further support the presence of a left-lateralized P3 deficit in SPD. Biol Psychiatry 2000; 48:702–705 © 2000 Society of Biological Psychiatry
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تاریخ انتشار 2000